Oral Copaxone
From MS Info Wiki
This medication is like Copaxone, except that oral Copaxone is taken in through the mouth in the form of a pill, instead of intravenously. In all cases, the four main MS drug therapies (Avonex, Betaseron, Copaxone, and Rebif) are given by intravenous injection. This is to avoid the breakdown of the drug within the gastrointestinal tract.
[edit] Study
- Teva Pharmaceuticals sponsored a study on oral Copaxone, called CORAL, which involved numerous universities around the world.
- The purpose of the study was to determine if oral Copaxone could reduce the rate of exacerbations and decrease the number of MS plaques.
- More than 1600 men and women with relapsing-remitting MS were involved in the trial.
- The results from the trial were not promising: no benefit was obtained from taking Copaxone orally, as compared to the placebo.
[edit] ASK MS Articles
- Oral Copaxone Interim Results Disappointing 1.4.1.28.s
- Small Study of Minocycline Shows Promise as MS Therapy 2.2.9.m
- Use of Oral Copolymer 1 for Experimental Allergic Encephalomyelitis (EAE) 1.4.1.28.i
[edit] Sources
“Coral Study Marks First Worldwide Trial for Oral MS Therapy.” Mult-Sclerosis.org. 25 Apr. 2000. 24 Jul. 2004 <http://www.mult-sclerosis.org/news/Apr2000/OralCopaxonex1.html>.
“MS: Completed Studies for Historical Reference.” Southcook Multiple Sclerosis Support. 2003. 24 Jul. 2004 <http://www.southcookms.org/trials/completed/index.cfm>.
Multiple Sclerosis Society of Canada. “Oral Copaxone Interim Results ‘Disappointing’.” Medical Update Memo. 24 Oct. 2001. 24 Jul. 2004 <http://www.mssociety.ca/en/research/DMT011024.htm>.
